Angiomiolipoma de cavidad nasal: reporte de un caso y revisión de la literatura / Angiomyolipoma of the nasal cavity: case report and literature review

El angiomiolipoma de cavidad nasal es un tumor hamartomatoso extremadamente infrecuente compuesto por adipocitos maduros, espacios vasculares con escaso tejido elástico y la presencia de haces de células musculares lisas maduras. Se manifiesta principalmente por obstrucción nasal unilateral y epistaxis recurrente. Se presenta el caso de una paciente de 73 años con historia crónica de obstrucción nasal y epistaxis recurrente izquierda asociada a rinorrea y descarga posterior intermitente. La tomografía computarizada (TC) y resonancia nuclear magnética (RNM) demuestran una lesión vascular circunscrita en fosa nasal izquierda. La angiografía demostró irrigación exclusiva de la arteria esfenopalatina izquierda. Se realizó extirpación de la lesión por abordaje endonasal endoscópico previa embolización arterial. La revisión de la literatura mundial muestra que es el duodécimo caso de angiomiolipoma de cavidad nasal reportado.

Angiomyolipoma of nasal cavity is an extremely rare hamartoma tumor composed of mature adipocytes, vascular spaces with lack of elastic tissue, and the presence of bundles of mature smooth muscle cells. It manifests itself mainly by unilateral nasal obstruction and recurrent epistaxis. We present the case of a 73-years-old woman with chronic history of left-sided nasal obstruction and recurrent epistaxis associated with rhinorrhea and intermittent post nasal drip. Computed tomography and magnetic resonance imaging demonstrate a vascular lesion inside the left nasal cavity. Angiography showed irrigation exclusively by the left sphenopalatine artery Surgical excision was performed by endoscopic endonasal approach after arterial embolization. World literature review showed that this is the twelfth reported case of angiomyolipoma of the nasal cavity.

Síndrome de Klippel-Feil con fistula traqueoesofagica, pulgar bifido y angiolipoma cerebral / Klippel-Feil syndrome with tracheoesophageal fistula, bifid thumb and cerebral angiolipoma

El síndrome de Klippel-Feil es una malformación congénita de la charnela cráneo-cervical compleja que involucra vértebras y visceras, caracterizada por la tríada clásica de cuello corto, limitación de movimientos de la cabeza por la fusión de vértebras cervicales e implantación baja del cabello en la región occipital. Se presenta por falla de segmentación en el esqueleto axial del embrión. Su incidencia se estima en 1/40 000-42 000nacimientos y predomina en el sexo femenino. El objetivo del presente trabajo es describir el cuadro clínico de un paciente con síndrome de Klippel-Feil y múltiples malformaciones asociadas, entre ellas, fístula traqueoesofágica, pulgar bífido y lipomas/angiolipomas intracraneales, las cuales, hasta ahora, no han sido descritas en el síndrome, por lo que se considera un hallazgo excepcional.

The Klippel-Feil syndrome is a congenital malformation of the skull flap involving complex cervical vertebrae and organs, characterized by a classic triad: short neck, limitation of movement of the head due to cervical spine fusion and low hairline in occipital region. It results from an error in the axial skeleton segmentation of the embryo; its incidence is estimated at 1/40,000-42,000 births and predominates in females. The aim of this paper is to describe the clinical picture of a patient with Klippel-Feil syndrome and multiple malformations, including tracheoesophageal fistula, bifid thumb and intracranial lipomas/angiolipomas,that have not been previously described in the syndrome, so it is considered an exceptional finding.

Angiolipoma intraóseo del calcáneo. Reporte de un caso y revisión de la literatura / Calcaneous intraosseous angiolipoma. A Case Report and literatura review

Los lipomas intraóseos son considerados como los tumores óseos primarios benignos más raros por su muy poca frecuencia. Su incidencia es menor del 1 por 1.000 entre los tumores primarios y para 2002 se habían publicado menos de 100 casos a nivel mundial. El angiolipoma, es una variante histológica del lipoma aún menos frecuente, representando sólo del 5 al 17% de todos los lipomas intraóseos. Generalmente se trata de una lesión asintomática, un hallazgo radiológico en exámenes realizados por otras razones suele ser la forma de su diagnóstico. Sin embargo, algunos lipomas pueden ser sintomáticos. Presentamos el caso de paciente femenino de 36 años quien posterior a presentar dolor del tobillo derecho se diagnostica una lesión en el calcáneo, que posterior a su análisis anatomopatológico resultó ser un angiolipoma intraóseo. Presentamos su tratamiento con médula ósea autóloga y su evolución(AU)

Intraosseous lipomas are considered the rarest and a very infrequently benign primary bone tumors. Its incidence is less than 1 per 1,000 between primary tumors and by 2002 had published fewer than 100 cases worldwide. The angiolipoma, is a histological variant of lipoma even rarer, representing only 5 to 17% of all intraosseous lipomas. This is usually an asymptomatic lesion, radiological finding in tests performed for other reasons is usually the way to diagnosis. However, some may be symptomatic lipomas. We report the case of a female patient aged 36 who after presenting pain in the right calcaneus, which after pathologic analysis proved diagnosed intraosseous angiolipoma. We present treatment with autologous bone marrow and evolution(AU)

MRI Features of Spinal Epidural Angiolipomas

OBJECTIVE: To describe the MRI findings in ten patients of spinal epidural angiolipoma for differentiated diagnosis presurgery. MATERIALS AND METHODS: Ten surgically proved cases of spinal epidural angiolipomas were retrospectively reviewed, and the lesion was classified according to the MR findings. RESULTS: Ten tumors were located in the superior (n = 4), middle (n = 2), or inferior (n = 4) thoracic level. The mass, with the spindle shape, was located in the posterior epidural space and extended parallel to the long axis of the spine. All lesions contained a fat and vascular element. The vascular content, correlating with the presence of hypointense regions on T1-weighted imaging (T1WI) and hyperintense signals on T2-weighted imaging, had marked enhancement. However, there were no flow void signs on MR images. All tumors were divided into two types based on the MR features. In type 1 (n = 3), the mass was predominantly composed of lipomatous tissue (> 50%) and contained only a few small angiomatous regions, which had a trabeculated or mottled appear. In type 2 (n = 7), the mass, however, was predominantly composed of vascular components (> 50%), which presented as large foci in the center of the mass. CONCLUSION: Most spinal epidural angiolipomas exhibit hyperintensity on T1WI while the hypointense region on the noncontrast T1WI indicates to be vascular, which manifests an obvious enhancement with gadolinium administration.

Unusual Case of Sialoangiolipoma.

Sialoangiolipoma is extremely rare in adults. We report a case with an extremely unusual and atypical presentation of sialangolipoma of submandibular gland. The diagnosis of which is done on histopathology in a case with high index of clinical suspicion of pleomorphic adenoma.

Angiomiolipoma renal / Renal angiomiolypoma

El angiomiolipoma renal es un tumor benigno mesenquimático, poco frecuente. Constituye sólo del 2 al 6% de los tumores renales. Se presentan dos casos clínicos que fueron hallazgos incidentales en un estudio ecográfico. Se describen las posibles imágenes ecográficas en base al predominio de sus componentes (grasa, músculo liso y vasos sanguíneos). La conducta terapéutica dependerá del tamaño y de la clínica que ocasione.

Angiomiolipoma renal masivo como causa de sangrado retroperitoneal espontáneo / Massive renal angiomyolipoma as a cause of spontaneous retroperitoneal bleeding

Introducción: El angiomiolipoma (AML) es un tumor renal benigno, compuesto por una cantidad variable de tejido adiposo, músculo liso y vasos sanguíneos; que habitualmente crece dentro del espacio perinéfrico y suele complicarse con hemorragia intratumoral y menos frecuentemente perinéfrica y retroperitoneal, la cual se encuentra condicionada por el tamaño de la lesión. Objetivos: Evaluar dentro de las diferentes causas de sangrado retroperitoneal espontáneo al AML masivo, en confrontación con otras causas. Material y Métodos: Se estudiaron 3 pacientes con AML masivo previamente desconocidos y sangrado retroperitoneal. Dos de ellos fueron estudiados con resonancia magnética, en secuencias de T1 SE, T2 TSE con supresión grasa, T1 TSE con supresión grasa sin y con gadolinio. Uno fue estudiado con tomografía computada (TC) pre y post administración de contraste EV. Resultados: De los 3 pacientes estudiados, todos presentaron masas renales cuyos tamaños variaron entre 10 y 26 cm. De diámetro mayor, las cuales presentaron sangrado intratumoral y retroperitoneal de jerarquía. Conclusión: El AML masivo como causante de hemorragia retroperitoneal espontánea es por lo tanto una patología a tener en cuenta.

Angiolipoma espinal extradural. Reporte de un caso clínico de presentación en el embarazo / Extradural spinal angiolypoma. Report of a clinical case in pregnancy

Spinal Extradural Angiolipomas (SEA) are benign and rare tumors that may clinically presents as subacute spinal cord compression syndrome. The diagnosis may be suspected by spinal MRI, where fat suppression techniques are important to. Usually ,the lesion is amenable to total surgical excision and the functional prognosis is good. Histopathologically consist in a adipose cell matrix intermixed with vascular endothelial channels. We present a case of an thoracic SEA, whose was clinically evident during pregnancy. A literature review is made and the relationships between SEA and pregnancy are discussed as well as the main diagnostic and therapeutic approaches of this lesion.

Lumbosacral angiolipoma: case report

We present a case of a 46-year old woman with a ventral epidural angiolipoma at the lumbosacral level with erosion of the sacrum. About ninety cases of spinal angiolipomas have been previously described in the literature, most of them situated on the thoracic region, dorsal to the dural sac. Angiolipomas can be radically excised with a good prognosis even in the presence of bone erosion. We did not find any other angiolipoma at the sacral level surgically explored in the review of the literature

Breast angiolipoma: mammographic, sonographic and duplex doppler characters

The aim of this study was to show the mammographic, sonographic and duplex Doppler characteristics of angiolipoma. Ten cases, all were females with age range 45-70 years, were collected over a period of four years. All the patients were subjected to mammographic, ultrasonographic and duplex Doppler examinations. The mammographic characters of the masses were ill-defined nodule which was homogenously dense in six cases and showed central lucent area in three cases. The ultrasonographic examination revealed well-defined nodule, oval in shape, with normal appearance of skin, nipple and subcutaneous tissues. The masses were homogenously hyperechoic in seven cases, while central hypoechoic areas were seen in three cases. No posterior acoustic enhancement was seen in nine cases. Duplex Doppler examination showed benign characters. The ultrasonographic appearance could share in the documentation of another benign lesion when a hyperechoic well-defined mass is encountered on breast ultrasonography

Tumores cutáneos dolorosos: primera parte / Painful cutaneous tumors: first part

El prurito es probablemente el síntoma predominante en la práctica dermatológica. El dolor es menos frecuente. No obstante, hay un conjunto de lesiones tumorales de la piel que tienen sintomatología dolorosa de variada intensidad. En este artículo se describen las características de estas lesiones dermatológicas potencialmente dolorosas: angiolipoma, condrodermatitis nodularis, dermatofibroma, endometriosis cutánea, espiradenoma ecrino y leiomioma. Se presenta un caso de cada una de estas entidades clínicas con sus respectivas histopatologías

Angiolipoma mastoídeo / Mastoid angiolipoma

Se presenta una paciente de 38 años con antecedentes de haber sido operada de una mastoidectomía radical de su oído izquierdo. Por presentar cefalea persistente de tres meses de evolución su médico neurólogo le solicita una tomografía computada la que se informa como un colesteatoma derecho. Se diagnostica una cefalea tensional y por su compromiso otológico se envía en interconsulta al otorrinolaringólogo. Es estudiada en el Servicio y con el diagnóstico de presunto colesteatoma se realiza una operación de mastoidectomía radical derecha encontrándose en la mastoides una masa con aspecto graso cuyo diagnóstico histopatológico es de angiolipoma. La investigación bibliográfica hecha al respecto sólo ha encontrado tres casos clínicos de lipomas del oído medio siendo el caso que publicamos el primer caso de angiolipoma informado en una publicación médica. Se discute y comenta aspectos clínicos, etiológicos y pronósticos sobre este raro tumor que se presenta excepcionalmente en el oído medio

Angiomiolipoma renal / Kidney angiomiolipoma

We report a fifty threes years old female patient, who suffered right lumbar pain, total hematuria and palpable abdominal mass. An abdominal T.A.C. showed a right renal tumor of fat density. Renal Angiomiolipoma an teratoma were considered among neoformative processes. It wasn't found any tumor's extension. Radical nefrectomy was done. The histopatologic diagnosis was renal angiomiolipoma.

Angiolipoma of suprasellar region.

An angiolipoma of the suprasellar region occurred in an 8-year-old boy. Review of 5 intracranial angiolipomas, including the current case, revealed that four were in the sellar region of one man and three women. One was in the thalamus of a man. The average age of the patients was 49 years, and average size of the tumors was 2.5 cm across. The angiolipomas associated with the sellar region often created abnormalities of the eye viz exophthalmos, decreased vision, and palsy of the oculomotor nerve. Sudden onset has ensued in a massively hemorrhagic thalamic angiolipoma. The characteristic low density with negative Hounsfield unit values in CT scan and hyperdensity in MRI of the brain suggested adipose tissue component of the angiolipoma. The angiography has depicted the angiomatous component of the latter. The combined characteristic CT scan, MRI, and angiographic features should demonstrate both vascular and adipose tissue elements of the angiolipomas before pathologic examination.

Angiolipoma epidural torácico: relato de caso / Thoracic epidural angiolipoma: report of a case

Angiolopomas da coluna vertebral constituem neoplasias raras (40 casos descritos na literatura). Em sua maioria estes tumores säo epidurais, apresentam características benignas, contendo elementos vasculares e elementos adiposos maduros. A sintomatologia é inespecífica, mas a tomografia computadorizada e principalmente a ressonância eletromagnética permitem fazer o diagnóstico com precisäo, como exemplifica o caso relatado

Angiolipoma intrarraquidiano: relato de caso / Spinal angiolipoma: case report

O angiolipoma intrarraquidiano, apesar de infrequente (0,14 por cento de todos os tumores do eixo espinhal), pode apresentar morbidade acentuada quando näo tratado convenientemente e a tempo. Sua lenta evoluçäo e a pobreza de sintomatologia podem mimetizar doenças degenerativas e/ou inflamatórias. Os autores relatam um caso, revisam a literatura disponivel e tecem consideraçöes sobre a fisiopatogenia desta doença, além de aspectos epidemiológicos, clínicos e radiológicos